Independent Predictors of Low Cardiac Output in Patients Undergoing Cabg Surgery

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Abstract

Background The low output syndrome is one of the most important potential complications for coronary artery by-pass grafting procedures. Therefore, the aim of this study was to analyze the baseline characteristics of surgical patients, the incidence of this syndrome, the outcome, as well, as its clinical predictors. Methods 1293 patients, from 41argentine centers, undergoing coronary artery bypass grafting- as an isolated procedure were prospectively included. Potential predictors for low output syndrome were analyzed through a logistic regression model. Results The incidence of low output syndrome was 17.1% with an overall mortality of44.6%. By univariate analysis, female gender, age older than 70 years; unstable angina and moderate to severe left ventricular function impairment were associated withl ow output syndrome. After potential confounders were balanced through multivariate analysis, some of the above mentioned variables maintained their predictive value: female gender (OR =1.61, CI 95%= 1.10-2.34), age older than 70 years (OR =2, CI 95%= 1.41-2.82) and severe left ventricular function impairment (OR =3.53, CI 95% = 2.21-5.69). Conclusions In patient undergoing coronary artery bypass grafting as an isolated procedure the incidence of low output syndrome was 17.1%. The overall mortality for patients presenting this complication was 44.6% .Female gender, age>70 and severe left ventricular function impairment were independent predictors of low output syndrome.